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1 πικραίνω
πικραίνω fut. πικρανῶ; aor. ἐπίκρανα LXX. Pass: fut. 3 pl. πικρανθήσονται Jer 40:9; 1 aor. ἐπικράνθην; prim. ‘make sharp’ esp. to the taste (s. three next entries).① to cause to become bitter, make bitter in physical sense (Hippocr. et al.) πικρανεῖ σου τὴν κοιλίαν (κοιλία 1b) Rv 10:9. Pass., of the stomach ἐπικράνθη ἡ κοιλία vs. 10. Of someth. that has been swallowed: (τὰ ὕδατα) ἐπικράνθησαν 8:11 (prob. not in ref. to οἱ ἄνθρωποι, in the sense ‘made bitter’=poisoned?). Of honey when wormwood is mixed w. it Hm 5, 1, 5.② to cause bitter feelings, embitter, make bitter, in affective sense (Pla.+; LXX; ApcrEzk Denis p. 122, 3 [Epiph. 70, 14]) pass., intr. sense become bitter or embittered abs. (Demosth., Ep. 1, 6; Ep. 6 of Apollonius of Tyana: Philostrat. I 346, 19; Is 14:9; Philo, Mos. I, 302) Hm 10, 2, 3. π. πρός τινα be embittered against someone Col 3:19 (πρός τινα as Lynceus in Athen. 6, 242b).—DELG s.v. πικρός. M-M. TW.
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